Author

A. Furness

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1

Frequent Co-Authors

T. Marafioti· 3 shared S. Quezada· 2 shared A. Akarca· 1 shared A. Bryant· 1 shared A. Chakravarthy· 1 shared A. Feber· 1 shared A. Pennycuick· 1 shared A. Sadanandam· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

T. Marafioti

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Author profile →

3 papers

Recent·Most cited

Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer

A. Pennycuick, V. H. Teixeira, K. AbdulJabbar, S. E. A. Raza, T. Lund, A. Akarca, R. Rosenthal, C. P. Pipinikas, H. Lee-Six, D. P. Chandrasekharan, R. E. Hynds, K. H. C. Gowers, J. Y. Henry, C. Denais, M. Falzon, , S. M. Janes

The paper investigates immune surveillance in pre-invasive squamous cell lung cancer, finding that regressive lesions have more immune infiltration and distinct molecular profiles compared to progressive lesions.

bioRxiv · Nov 10, 2019Cancer Biology

Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer

A. Woolston, K. Khan, G. Spain, L. J. Barber, B. Griffiths, R. Gonzalez Exposito, Y. Patil, S. Mansukhani, M. N. Davies, A. Furness, F. Sclafani, C. Peckitt, K. Kouvelakis, R. Ranftl, R. Begum, , M. Gerlinger

The paper analyzes genomic and transcriptomic data from CRC patients treated with cetuximab to identify resistance mechanisms and immune landscape changes during anti-EGFR therapy.

bioRxiv · Oct 19, 2018Cancer Biology

Pan-cancer deconvolution of cellular composition identifies molecular correlates of antitumour immunity and checkpoint blockade response

A. Chakravarthy, A. Furness, K. Joshi, E. Ghorani, K. Ford, M. J. Ward, E. V. King, M. Lechner, T. Marafioti, S. Quezada, G. J. Thomas, A. Feber, T. Fenton

This study identifies immune hot and cold tumour subgroups across cancers using DNA methylation-based deconvolution, linking them to immunotherapy response and immune resistance mechanisms.

bioRxiv · Mar 13, 2018Cancer Biology