Author

G. Janssen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. D. Hollander· 1 shared A. I. Costa· 1 shared A. Mulder· 1 shared C. Chatterjee· 1 shared C. Schiesswohl· 1 shared E. Stratikos· 1 shared E. Wiertz· 1 shared F. Claas· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. D. Hollander

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Proinsulin degradation and presentation of a proinsulin B-chain autoantigen involves ER-associated protein degradation (ERAD)-enzyme UBE2G2

T. Cremer, H. Hoelen, M. L. van de Weijer, G. Janssen, A. I. Costa, P. van Veelen, R. J. Lebbink, E. Wiertz

This study identifies UBE2G2 as a key enzyme in the ERAD-mediated degradation of proinsulin, leading to the presentation of a proinsulin B-chain autoantigen in T1D.

PLOS ONE · May 24, 2024Peer-reviewedCell Biology

ERAP2 increases the abundance of a peptide submotif highly selective for the Birdshot Uveitis-associated HLA-A29

W. Venema, S. Hiddingh, J. H. de Boer, F. Claas, A. Mulder, A. D. Hollander, E. Stratikos, S. Sarkizova, L. v. d. Veken, G. Janssen, P. v. Veelen, J. J. Kuiper

The paper investigates how ERAP2 affects HLA-A29 peptide presentation in BU and identifies an HLA-A29-specific peptide motif linked to autoantigens.

bioRxiv · Aug 14, 2020 · PreprintImmunology

Discovery and Optimization of Inhibitors for the Pup Proteasome System in Mycobacterium tuberculosis

G. Janssen, R. Merkx, S. Zhang, C. Schiesswohl, C. Chatterjee, H. Darwin, H. Ovaa

This study identifies and optimizes inhibitors of the Pup proteasome system in M. tuberculosis through high-throughput screening and SAR analysis.

bioRxiv · Oct 7, 2019 · PreprintMicrobiology