Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
T. Cremer, H. Hoelen, M. L. van de Weijer…·E. Wiertz
This study identifies UBE2G2 as a key enzyme in the ERAD-mediated degradation of proinsulin, leading to the presentation of a proinsulin B-chain autoantigen in T1D.
S. Zheng, H. de Buhr, P. Praest…·R. J. Lebbink
This study identifies SARS-CoV-2 ORF7a as a viral factor that downregulates MHC class I surface expression, impairing antigen presentation and immune surveillance.
V. T. K. Le-Trilling, S. Banchenko, D. Paydar…·D. Schwefel
This study identifies E27 as a viral protein that targets STAT2 for degradation via CRL4 ubiquitin ligases, revealing its structural mechanism of interferon antagonism.
W. Nijenhuis, H. G. J. Damstra, E. J. van Grinsven…·L. C. M. Kapitein
This study uses advanced microscopy to show how SARS-CoV-2 changes the structure of human airway cells at the subcellular level.
M. van der Vlist, M. I. Pascoal Ramos, L. L. van den Hoogen…·L. Meyaard
This study shows that type I interferon alters CD200R signaling by promoting RasGAP cleavage, converting CD200R from an inhibitor to a potentiator of IFNG mRNA production in SLE patients.
A. B. Schuren, I. G. J. Boer, E. Bouma…·E. Wiertz
The paper shows that genetic disruption of SEC61, SEC62, and SEC63 affects human cytomegalovirus US2 expression, specifically dependent on its signal peptide.