MicrobiologybioRxiv
Comparative Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus despite strain-dependent differences in essentiality of shared cell envelope genes
K. A. Coe, W. Lee, G. Komazin-Meredith…·S. Walker
This paper uses Tn-Seq to compare gene essentiality across multiple S. aureus strains, identifying common resistance determinants and strain-dependent differences under daptomycin exposure.
DOI 10.1371/journal.ppat.1007862