Author

G. Kops

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Janssen· 1 shared A. Perrakis· 1 shared A. Quirindongo· 1 shared A. Teixeira· 1 shared B. Snel· 1 shared E. Tromer· 1 shared G. Spyroulias· 1 shared H. Ma· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Janssen

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Author profile →

3 papers

Recent·Most cited

The MPS1 kinase NTE region has helical propensity and preferred conformations towards the TPR domain

Y. Hiruma, M.-T. Matsoukas, W. Touw, G. Spyroulias, G. Kops, M. Ubbink, A. Perrakis

This study investigates the conformational dynamics of the MPS1 kinase NTE region relative to the TPR domain using paramagnetic NMR and Rosetta, revealing helical propensity and convex surface interactions.

bioRxiv · Mar 31, 2020 · PreprintBiochemistry

Degree and site of chromosomal instability define its oncogenic potential

W. Hoevenaar, A. Janssen, A. Quirindongo, H. Ma, S. Klaasen, A. Teixeira, J. Offerhaus, R. Medema, G. Kops, N. Jelluma

This study shows that chromosomal instability (CIN) can drive early-onset intestinal adenomas, with varying effects depending on CIN levels and tissue site.

bioRxiv · Dec 15, 2019Cancer Biology

Mosaic origin of the eukaryotic kinetochore

J. J. van Hooff, E. Tromer, G. Kops, B. Snel

This study identifies the origin of the eukaryotic kinetochore by analyzing its protein composition and evolutionary history, revealing a mosaic origin involving both prokaryotic and eukaryotic proteins.

bioRxiv · Jan 8, 2019Cell Biology