Optogenetic currents in myofibroblasts acutely alter electrophysiology and conduction of co-cultured cardiomyocytes
G. Kostecki, Y. Shi, C. S. Chen, D. H. Reich, E. Entcheva, L. Tung
This study shows that optogenetic activation of myofibroblasts in co-cultures with cardiomyocytes reduces conduction velocity and shortens action potential duration, indicating electrical coupling between cell types.
bioRxiv · Jun 2, 2020Physiology