PhysiologybioRxiv
Optogenetic currents in myofibroblasts acutely alter electrophysiology and conduction of co-cultured cardiomyocytes
G. Kostecki, Y. Shi, C. S. Chen…·L. Tung
This study shows that optogenetic activation of myofibroblasts in co-cultures with cardiomyocytes reduces conduction velocity and shortens action potential duration, indicating electrical coupling between cell types.
DOI 10.1038/s41598-021-83398-4