Author

G. Minervini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

S. C. E. Tosatto· 5 shared F. Quaglia· 2 shared F. Tabaro· 2 shared A. Falconieri· 1 shared A. Rasola· 1 shared C. Laquatra· 1 shared C. Sanchez-Martin· 1 shared D. Piovesan· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersCancer Biology

S. C. E. Tosatto

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Author profile →

5 papers

Recent·Most cited

Patient-specific simulation of Retinal Hemangioblastoma provides new perspectives on the role ofantiangiogenic therapy

F. Pradelli, G. Minervini, S. C. E. Tosatto

The paper uses a mathematical model to simulate Retinal Hemangioblastoma (RH) and shows that angiogenesis occurs rapidly once the tumor reaches a critical mass, suggesting antiangiogenic therapy may be ineffective once diagnosed.

bioRxiv · Feb 24, 2023 · PreprintCancer Biology

HIF1a-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia

A. Rasola, C. Laquatra, C. Sanchez-Martin, G. Minervini, E. Moroni, M. Schiavone, S. C. E. Tosatto, F. Argenton, G. Colombo, P. Bernardi, I. Masgras

This study identifies TRAP1 as a HIF1a-dependent regulator of mitochondrial bioenergetics in hypoxic conditions, showing its role in maintaining respiration in developing embryos and cancer models.

bioRxiv · Sep 23, 2020Biochemistry

The E3 ubiquitin-protein ligase MDM2 is a novel interactor of the von Hippel-Lindau tumor suppressor

A. Falconieri, G. Minervini, R. Bortolotto, D. Piovesan, R. Lopreiato, G. Sartori, M. Pennuto, S. C. E. Tosatto

This study identifies a novel interaction between pVHL30 and MDM2, showing isoform-specific binding and functional synergy in cell proliferation regulation.

bioRxiv · Apr 28, 2020Biochemistry

Insights into the molecular features of the von Hippel-Lindau like protein

F. Quaglia, G. Minervini, F. Tabaro, S. C. E. Tosatto

This study characterizes the von Hippel-Lindau like protein (VLP) through in silico methods, showing its structural similarity to pVHL and potential functional overlap.

bioRxiv · Sep 3, 2018Cancer Biology

Genotype-Phenotype Relations of the von Hippel-Lindau Tumor Suppressor Inferred from a Large-Scale Analysis of Disease Mutations and Interactors

G. Minervini, F. Quaglia, F. Tabaro, S. C. E. Tosatto

This paper analyzes VHL mutations and interactors to identify genotype-phenotype relationships and predict tumor transformation mechanisms.

bioRxiv · Aug 31, 2018Cancer Biology