Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells
Y. Zhang, R. Tedja, M. Millman, T. Wong, A. Fox, H. Chehade, M. Gershater, N. Adzibolosu, R. Gogoi, M. Anderson, T. Rutherford, Z. Zhang, M. Chopp, G. Mor, A. B. Alvero
This study identifies adipose-derived exosomal miR-421 as a regulator of CBX7 expression, promoting ovarian cancer metastasis by inducing epigenetic changes.
bioRxiv · Nov 7, 2023Cancer Biology