Pharmacology & ToxicologybioRxivPreprint
Hydroquinone, a cigarette smoke compound, affects cartilage homeostasis through activation of the aryl hydrocarbon receptor pathway.
C. S. Heluany, A. de Palma, N. J. Day…·G. Nalesso
This study shows hydroquinone, a cigarette smoke compound, harms cartilage by activating the AhR pathway, reducing SOX-9 and Col2a1 while increasing MMP-3 and ADAMTS5.
DOI 10.1101/2022.04.25.489372