Author

G. Rogler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. Misselwitz· 4 shared A. Wyss· 3 shared M. R. Spalinger· 3 shared M. Scharl· 3 shared T. Raselli· 3 shared A. Mookhoek· 1 shared A. Telzerow· 1 shared A. W. Sailer· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

B. Misselwitz

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Development of non-alcoholic steatohepatitis is associated with gut microbiota but not oxysterol synthesis

J. Wyss, T. Raselli, A. Wyss, A. Telzerow, G. Rogler, N. Krupka, B. Yilmaz, T. S. Schmidt, B. Misselwitz

This study investigates the role of gut microbiota and the EBI2-oxysterol axis in NASH development using a mouse model, finding microbiota differences but no link between the EBI2 axis and microbiota.

bioRxiv · Dec 2, 2022 · PreprintMicrobiology

Temperature-triggered in situ forming lipid mesophase gel for local treatment of ulcerative colitis

M. Carone, M. R. Spalinger, R. A. Gaultney, A. Mookhoek, P. Krebs, G. Rogler, P. Luciani, S. Aleandri

This study develops a temperature-triggered in situ forming lipid gel for topical treatment of ulcerative colitis, showing reduced inflammation in preclinical models.

bioRxiv · Sep 28, 2022Bioengineering

Co-cultivation is a powerful approach to produce a robust functionally designed synthetic consortium as a live biotherapeutic product (LBP)

F. Kurt, G. E. Leventhal, M. R. Spalinger, L. Anthamatten, P. Rogalla von Bieberstein, G. Rogler, C. Lacroix, T. de Wouters

This study designs a synthetic microbial consortium through co-cultivation and shows it is as effective as fecal microbiota transplants in treating colitis.

bioRxiv · Oct 13, 2021Microbiology

The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis

A. Wyss, T. Raselli, G. Schmelczer, G. Klinke, N. Perkins, M. Hersberger, M. R. Spalinger, K. Atrott, S. Lang, I. Frey-Wagner, M. Scharl, A. W. Sailer, O. Pabst, G. Rogler, B. Misselwitz

This study shows that the EBI2-7,25-dihydroxycholesterol axis is induced in colitis and promotes lymphoid structure accumulation during homeostasis and inflammation.

bioRxiv · Sep 24, 2018Immunology

Microbiota stability in healthy individuals after single-dose lactulose challenge - a randomized controlled study

S. Y. Wotzkas, M. Kreuzer, L. Maier, M. Zuend, M. Schlumberger, B. Nguyen, M. Fox, D. Pohl, H. Heinrich, G. Rogler, L. Biedermann, M. Scharl, S. Sunagawa, W.-D. Hardt, B. Misselwitz

This study examines the effect of a single-dose lactulose challenge on gut microbiota stability and E. coli density in healthy individuals, finding no significant changes in E. coli levels or microbiota composition.

bioRxiv · Sep 24, 2018Microbiology

The oxysterol synthesizing enzyme CH25H contributes to the development of intestinal fibrosis

T. Raselli, A. Wyss, M.N. Gonzalez Alvarado, B. Weder, C. Mamie, M.R. Spalinger, W. T. van Haaften, G. Dijkstra, A.W. Sailer, P.H. Imenez Silva, C.A. Wagner, V. Tosevski, Sebastian Leibl, M. Scharl, G. Rogler, , B. Misselwitz

This study shows that the oxysterol synthesizing enzyme CH25H contributes to intestinal fibrosis in Crohn's disease by promoting collagen deposition and fibroblast activity.

bioRxiv · Sep 23, 2018 · PreprintImmunology