G. Tedeschi

ESPRESSO: Spatiotemporal omics based on organelle phenotyping

ESPRESSO provides high-dimensional spatiotemporal phenotyping of organelles using fluorescent labeling and advanced microscopy, enabling analysis of cell states, stress response, and immune cell polarization.

Monitoring macrophage polarization with gene expression reporters and bioluminescence phasor analysis

This study develops bioluminescent reporters to monitor macrophage polarization in real-time with single-cell resolution in 2D and 3D environments.

Multimodal Phasor Approach to study breast cancer cells invasion in 3D spheroid model

The paper uses a multimodal imaging approach to study breast cancer cell invasion in 3D spheroids, quantifying changes in metabolism, fatty acid storage, and collagen organization over time.