Author

G. Tornillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

H. Kendrick· 3 shared M. J. Smalley· 3 shared A. T. Higgins· 1 shared C. Chabbert· 1 shared E. J. Davies· 1 shared H. Morgan· 1 shared J. Bradford· 1 shared K. R. Greenow· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

H. Kendrick

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Author profile →

3 papers

Recent·Most cited

Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model

G. Tornillo, L. Warrington, H. Kendrick, A. T. Higgins, T. Hay, S. Beck, M. J. Smalley

The paper examines the role of LYN kinase in BRCA1-defective mammary tumours, finding minimal impact on tumour formation but suggesting B-cell infiltration may influence growth.

bioRxiv · Mar 23, 2023 · PreprintCancer Biology

Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model

L. D. Ordonez, L. Melchor, K. R. Greenow, H. Kendrick, G. Tornillo, J. Bradford, P. Giles, M. J. Smalley

The paper shows that reproductive history influences HER2-driven breast cancer tumour subtypes through locus amplification and WNT signalling activation in a mouse model.

bioRxiv · Oct 30, 2020Cancer Biology

Generation and characterisation of an estrogen receptor-positive GEMM-derived Pten p53 null transplantable breast tumour model for therapeutic testing

E. J. Davies, H. Morgan, G. Tornillo, C. Chabbert, H. Kendrick, M. J. Ahdesmaki, S. Luke, S. T. Barry, M. J. Smalley

The paper develops a transplantable breast tumour model from an ER+ GEMM to study therapeutic resistance and pathway dependencies in breast cancer.

bioRxiv · Sep 12, 2019 · PreprintCancer Biology