Cancer BiologybioRxiv
Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
L. D. Ordonez, L. Melchor, K. R. Greenow…·M. J. Smalley
The paper shows that reproductive history influences HER2-driven breast cancer tumour subtypes through locus amplification and WNT signalling activation in a mouse model.
DOI 10.1242/dmm.048736