BiophysicsbioRxiv
Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain
J. Newton, G. Y. Li, M. T. Naik…·G. Jogl
This paper shows that the N-terminus and coiled-coil domain of ORF1 protein mediate phase separation, which may protect L1 transcripts from degradation.
DOI 10.1016/j.bpj.2021.03.028