NeurosciencebioRxivPreprint
Concerted cellular responses to type I interferon propel memory impairment associated with amyloid β plaques
Ethan R. Roy, Gabriel S. Chiu, Sanming Li…·Wei Cao
This study identifies type I interferon signaling as a key driver of memory impairment in Alzheimer's disease by promoting neuroinflammation and synaptic loss in a mouse model.
DOI 10.1101/2021.11.01.466525