BioengineeringBonePeer-reviewed
Hindlimb Unloading Induces Bone Microarchitectural and Transcriptomic Changes in Murine Long Bones in an Age-Dependent Manner
Steven J. Meas, Gabriella M. Daire, Michael A. Friedman…·Henry J. Donahue
This study shows that hindlimb unloading causes age-dependent changes in bone microarchitecture and gene expression in mice, with younger mice showing senescence pathway activation and older mice showing mitochondrial dysfunction.
5 citations