Cell BiologybioRxivPreprint
The architecture of the endoplasmic reticulum is regulated by the reversible lipid modification of the shaping protein CLIMP-63
Patrick A. Sandoz, Robin A. Denhardt-Eriksson, Laurence Abrami…·F. Gisou van der Goot
This paper shows that ZDHHC6-mediated S-palmitoylation of CLIMP-63 regulates ER morphology by controlling its localization and abundance in mammalian cells.