Author

Gauri G. Bora

Northwestern University

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Synthetic Biology· 1

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Organism:mouse· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

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Anh V NguyenORCID

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedFeb 13, 2026

GCAD: a Computational Framework for Mammalian Genetic Program Computer-Aided Design

Kathleen S. Dreyer, Anh V Nguyen, Gauri G. Bora…·Niall M. Mangan

This paper introduces a computational framework for designing mammalian genetic programs using genetic algorithms and dynamical systems models, demonstrating its ability to find optimal circuit designs and validate them experimentally.

DOI 10.1021/acssynbio.5c00670

mousestatistical model

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