Author

Genta Chiba

The University of Tokyo

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Systems Biology· 1

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Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

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Arisa OdaiD· 1 shared Ken-ichiro F. KameiiD· 1 shared Kunihiro OhtaiD· 1 shared Yuichi WakamotoiD· 1 shared

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Systems BiologybioRxivPreprintMay 26, 2025

Global propagation of genetic perturbation effects through genome-wide stoichiometry conservation architecture

Genta Chiba, Ken-ichiro F. Kamei, Arisa Oda…·Yuichi Wakamoto

The paper shows that genetic perturbations affect genes maintaining stoichiometry with the perturbed gene, revealing a multi-level stoichiometry-conserving architecture across species.

DOI 10.1101/2025.05.26.656078

bacteria (other)human

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