Author

Geoffrey Zhao

Mayo Clinic

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

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Daniel D. BilladeauiD· 1 shared Emilia Rae DellaceccaiD· 1 shared Fabrice LucieniD· 1 shared Haidong DongiD· 1 shared Henrique Borges da SilvaiD· 1 shared Jacob B. HirdleriD· 1 shared Jacob J. TeskeiD· 1 shared Joanina K. GicobiiD· 1 shared

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1 shared paperImmunology

Daniel D. BilladeauORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJan 18, 2025

PD-1 prelimits both the cytotoxic and exhaustion potential in thymic CD8+ T cells and impacts the maintenance of peripheral tumor immunity

Zhiming Mao, Jacob B. Hirdler, Joanina K. Gicobi…·Haidong Dong

This study identifies PD-1's role in regulating effector potential and exhaustion in thymic CD8+ T cells, showing that PD-1 inhibition enhances expansion but leads to exhaustion in tumor tissues.

1 citation

mousebulk RNA-seq

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