Author

Giovanni Gonzalez-Gutierrez

Indiana University;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Adam ZlotnickiD· 1 shared Balasubramanian VenkatakrishnaniD· 1 shared Joseph Che-Yen Wang· 1 shared Khuchtumur Bum-ErdeneiD· 1 shared Mona K GhozayeliD· 1 shared Samy MerouehiD· 1 shared Zhongchao Zhao· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperBiophysics

Adam ZlotnickORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintNov 4, 2026

Fragment Covalent Bond Formation at SOS1 Tyr-884 Inhibits KRAS Nucleotide Exchange

Khuchtumur Bum-Erdene, Giovanni Gonzalez-Gutierrez, Mona K Ghozayel, Samy Meroueh

This paper identifies a covalent inhibitor of SOS1-KRAS binding by screening fragments that form bonds at Tyr-884, showing time- and concentration-dependent inhibition of KRAS nucleotide exchange.

DOI 10.64898/2026.11.01.763478

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiophysicsbioRxivPreprintJan 4, 2019

Structural Differences Between the Woodchuck Hepatitis Virus Core Protein in Dimer and Capsid States Indicate Entropic and Conformational Regulation of Assembly

Zhongchao Zhao, Joseph Che-Yen Wang, Giovanni Gonzalez-Gutierrez…·Adam Zlotnick

DOI 10.1101/512319

cryo-EMexperimental assay

𝕏 PostBluesky