Impaired Regulation of Redox Transcriptome during the Differentiation of iPSCs into Induced Cardiomyocytes (iCMs)
Gobinath Shanmugam, David Crossman, Johnson Rajasingh…·Namakkal S. Rajasekaran
The paper analyzes transcriptome changes during iPSC differentiation into iCMs and identifies impaired redox signaling and mitochondrial functions as critical factors affecting cell survival and cardiac regeneration.