Author

Eugenia V. Broude

University of South CarolinaORCID 0000-0002-9180-7111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Diana Akinyi OdhiamboiD· 2 shared Igor B. RoninsoniD· 2 shared Marina V AksenovaiD· 2 shared Mengqian CheniD· 2 shared Michael D. WyattiD· 2 shared Michael S. ShtutmaniD· 2 shared Vitali SikirzhytskiiD· 2 shared Abhyudai SinghiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Diana Akinyi OdhiamboORCID

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4 papers

Recent·Most cited

Cancer Biologynpj Breast CancerPeer-reviewedJan 17, 2026

Host-derived Interleukin 1α induces an immunosuppressive tumor microenvironment via regulating monocyte-to-macrophage differentiation

Manikanda Raja Keerthi Raja, Gourab Gupta, Grace Atkinson…·Hexin Chen

This study shows that host-derived IL-1α promotes an immunosuppressive tumor microenvironment by regulating monocyte-to-macrophage differentiation in breast cancer.

6 citationstop 2%

mousebulk RNA-seq

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Cancer BiologyJCI InsightPeer-reviewedJan 15, 2026

Anoikis resistance and metastasis of ovarian cancer can be overcome by CDK8/19 Mediator kinase inhibition.

Mehri Monavarian, Resha Rajkarnikar, Emily Faith Page…·Karthikeyan Mythreye

This study shows CDK8/19 inhibition can reverse anoikis resistance and metastasis in ovarian cancer by altering transcriptional programs.

5 citationstop 1%

humanbulk RNA-seq

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NeurosciencebioRxivPreprintSep 25, 2023

Suppression of HIV and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters

B. Celia Cui, Marina V Aksenova, Aliaksandra Sikirzhytskaya…·Michael S. Shtutman

This paper shows that 4-octyl-itaconate reduces HIV and cocaine-induced neurotoxicity and inflammation by modulating microglial activity and anti-inflammatory pathways.

2 citations

humanbulk RNA-seq

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NeuroscienceJournal of Neuroimmune PharmacologyPeer-reviewedDec 4, 2019

Inhibition of the Dead Box RNA Helicase 3 prevents HIV-1 Tat and cocaine-induced neurotoxicity by targeting microglia activation

Marina V Aksenova, Justin Sybrandt, Biyun Cui…·Michael S. Shtutman

This study identifies DDX3 inhibition as a potential therapy for HAND by blocking Tat and cocaine-induced microglial activation and neurotoxicity in rat and mouse models.

27 citations

ratmouse

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