Author

Guadalupe Guerrero-Serna

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Carlos Cruz-Cortés· 1 shared Jaroslava ŠeflováiD· 1 shared L. Michel Espinoza-Fonseca· 1 shared Seth L. RobiaiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperBiophysics

Carlos Cruz-Cortés

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintSep 7, 2023

Activation mechanism of the cardiac calcium pump by a small-molecule allosteric modulator

Jaroslava Šeflová, Carlos Cruz-Cortés, Guadalupe Guerrero-Serna…·L. Michel Espinoza-Fonseca

This study uses TCSPC imaging to show that CDN1163, a SERCA2a activator, synergizes with ATP to shift SERCA2a toward a competent conformation, enhancing its function under physiological conditions.

DOI 10.1101/2023.09.07.556734

microscopy & imaging analysisprotein folding & dynamics

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