Cancer BiologybioRxivPreprint
MIF-mediated reprogramming of myeloid lineage within the glioma tumor microenvironment impacts the efficacy of immune stimulatory gene therapy
Ziwen Zhu, Noah C Kanis, Anthony E George…·Maria Graciela Castro
This study identifies MIF-CD74 axis regulation of myeloid cells in gliomas and shows that MIF inhibition enhances immune therapy efficacy in wtIDH1 gliomas.