H. Antonicka

SLC25A46 is in contact with lysosomes and plays a role in mitochondrial cholesterol homeostasis

This study shows SLC25A46 is required for stress-induced mitochondrial hyperfusion and involved in mitochondrial cholesterol homeostasis.

BOLA3 and NFU1 link mitoribosome iron-sulfur cluster assembly to multiple mitochondrial dysfunctions syndrome

This study identifies BOLA3 and NFU1 as critical for mitoribosome iron-sulfur cluster assembly, linking their dysfunction to mitochondrial and metabolic disorders.

ESYT1 tethers the endoplasmic reticulum to mitochondria and is required for mitochondrial lipid and calcium homeostasis

This study identifies ESYT1 as a key protein tethering ER and mitochondria at MERCs, showing its role in calcium and lipid homeostasis.

SLC25A46 localizes to sites of mitochondrial fission and fusion and loss of function variants alter the oligomerization states of MFN2 and OPA1

This study investigates the role of SLC25A46 in mitochondrial dynamics, showing that its loss causes mitochondrial fragmentation and altered oligomerization of fusion proteins.

A high-density human mitochondrial proximity interaction network.

This paper creates a high-resolution human mitochondrial proximity interaction network using BioID, identifying 1465 proteins and 15626 interactions, revealing sub-compartment organization and functional modules.