H. Broetz-Oesterhelt

The paper discovers and characterizes two novel biaryl-containing lasso peptides, revealing new structural modifications and biosynthetic enzymes.

This study shows that CGlcN is metabolized into carba-metabolites that inhibit bacterial cell wall synthesis, revealing a new antimetabolite mechanism of action.

The paper quantifies and compares the passive transport of three aminoglycosides through different porins in E. coli, revealing varying permeation rates and confirming their relevance to antibiotic potency.

This paper identifies the composition of the Streptomyces Clp protease complex and reveals a new mechanism by which ADEP antibiotics accelerate proteolysis by binding to ClpP1 and Clp-ATPases.