Cell BiologybioRxiv
A Shape Sensing Mechanism driven by Arp2/3 and cPLA2 licenses Dendritic Cells for Migration to Lymph Nodes in Homeostasis
Z. Alraies, C. A. Rivera, M.-G. Delgado…·A.-M. Lennon-Dumenil
The paper identifies a shape sensing mechanism in dendritic cells that links cell motility to CCR7 expression, enabling migration to lymph nodes through ARP2/3-cPLA2 signaling.
DOI 10.1038/s41590-024-01856-3