Cancer BiologybioRxiv
Cholangiocytic differentiation drives cell proliferation in hepatoblastoma through Wnt-dependent FGF19 signaling
P. V. Wu, M. Fish, F. K. Hazard…·R. Nusse
The paper identifies FGF19 as a paracrine signal driving tumor growth in hepatoblastoma through Wnt-dependent mechanisms and biliary lineage activation.
DOI 10.1038/s41467-024-53802-4