Cell BiologybioRxivPreprint
PTK7 is a positive allosteric modulator of GPR133 (ADGRD1) signaling in GBM
J. D. Frenster, H. Erdjument-Bromage, W. Liu…·D. G. Placantonakis
This study identifies PTK7 as a positive allosteric modulator of GPR133 signaling in glioblastoma, showing that their interaction enhances receptor activation and is relevant to tumor pathogenesis.
DOI 10.1101/2022.06.15.496232