Cancer BiologybioRxiv
Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells
A.-K. Mattes, M. Puig Gamez, E. Martin…·L. K. Swee
The paper uses a complementary CRISPR screen to identify genes regulating tumor resistance to CTL killing, revealing contrasting roles of membrane-bound and soluble ICAM-1.
DOI 10.7554/elife.84314