BiochemistrybioRxiv
How a disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization
T. M. Gemeinhardt, R. M. Regy, T. M. Phan…·N. J. Francis
The paper investigates how a disordered linker in the Polyhomeotic protein influences phase separation and oligomerization in Drosophila and human cells through in vitro reconstitution and molecular dynamics simulations.
DOI 10.1016/j.molcel.2025.05.008