Cell BiologybioRxivPreprint
TET1 attenuates human pluripotency-related heterogeneities and enhances differentiation capabilities
M. Motono, K. Hiraki-Kamon, M. Kamon…·H. Kato
This study shows that adding TET1 to hiPSCs improves their differentiation capabilities and reduces heterogeneity by correcting DNA methylation and gene expression deviations.
DOI 10.1101/2022.04.29.489839