Author

H. L. Wright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. W. Edwards· 2 shared A. Clarke· 1 shared A. Filer· 1 shared A. L. Cross· 1 shared A. M. Thomas· 1 shared D. Windell· 1 shared E. Marin· 1 shared E. Pantazi· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

S. W. Edwards

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LAT1 enables T cell activation under inflammatory conditions: a new therapeutic target for rheumatoid arthritis

J. Ogbechi, H. L. Wright, S. Balint, L. Topping, K. Zec, I.-S. Huang, E. Pantazi, M. Swart, D. Windell, E. Marin, M. F. Wempe, H. Endou, A. M. Thomas, A. Filer, T. W. Stone, , R. Williams

This study shows LAT1 is critical for T cell activation in rheumatoid arthritis and identifies it as a therapeutic target, with a LAT1 inhibitor effective in mouse models.

bioRxiv · Dec 20, 2022 · PreprintImmunology

An improved culture protocol for the differentiation and survival of human promyelocytic leukaemia PLB-985 cell-line into mature neutrophil-like granulocytes

S. Shaayau, A. L. Cross, H. L. Wright, S. W. Edwards

This paper describes an improved culture protocol that differentiates the PLB-985 cell line into mature neutrophil-like granulocytes with enhanced survival and morphology.

bioRxiv · Sep 14, 2021 · PreprintImmunology

Type I Interferon regulates cytokine-delayed neutrophil apoptosis, reactive oxygen species production and chemokine expression via activation of p38 MAPK

L. Glennon-Alty, R. J. Moots, S. W. Edwards, H. L. Wright

This study shows Type I IFN modulates neutrophil apoptosis, ROS production, and chemokine expression through p38 MAPK activation, altering responses to inflammatory cytokines.

bioRxiv · Jun 30, 2020Immunology