Author

H. Lans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:DNA methylation· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. Marteijn· 3 shared A. Ray Chaudhuri· 2 shared B. Steurer· 2 shared C. Mukherjee· 2 shared D. Zhou· 2 shared J. Demmers· 2 shared M. van Toorn· 2 shared A. Houtsmuller· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

J. Marteijn

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Prolonged stalling of RNA Polymerase II at DNA damage explains phenotypical differences between Cockayne and UV-sensitive syndromes

C. Gonzalo Hansen, B. Steurer, R. C. Janssens, D. Zhou, M. van Sluis, H. Lans, J. Marteijn

This study shows that prolonged RNA Polymerase II stalling at DNA damage explains the differing phenotypes between Cockayne Syndrome and UV-sensitive Syndrome.

bioRxiv · May 17, 2023 · PreprintCell Biology

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

M. Geijer, D. Zhou, K. Selvam, B. Steurer, B. Evers, C. Mukherjee, S. Cugusi, M. van Toorn, M. van der Woude, W. Gong, R. Janssens, A. Raams, J. Lebbink, B. Geverts, D. Plummer, , J. Marteijn

This study identifies ELOF1 as a factor that promotes transcription-coupled repair and prevents genome instability by modulating transcription and recruiting repair factors.

bioRxiv · May 11, 2021Cell Biology

SMARCAD1 Mediated Active Replication Fork Stability Maintains Genome Integrity

C. Lo, M. van Toorn, V. Gaggioli, M. Paes Dias, Y. Zhu, E. Maria Manolika, W. Zhao, M. van der Does, C. Mukherjee, J. Souto Goncalves, M. van Royen, P. French, J. Demmers, I. Smal, H. Lans, , N. Taneja

This study identifies SMARCAD1 as a critical factor for replication fork stability, showing its role in preventing genome instability and enhancing resistance to replication poisons.

bioRxiv · Oct 5, 2020Cell Biology