Author

H. Leung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Greenland· 1 shared A. Laurena· 1 shared A. Varshney· 1 shared B. Gelfand· 1 shared B. Werner· 1 shared C. Stains· 1 shared E. Deomano· 1 shared E. Taylor· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperPlant Biology

A. Greenland

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3 papers

Recent·Most cited

Identifying Novel Candidate Defense Genes Against Rice Blast By Disease-Resistance Transcriptome Analysis

R. P. Mauleon, K. Satoh, V. Bartolome, M. Baraoidan, E. Deomano, S. Kikuchi, H. Leung

The paper identifies novel defense genes against rice blast by analyzing disease-resistance transcriptomes in mutant and resistant rice cultivars, finding correlated gene expression regions associated with resistance QTLs.

bioRxiv · Oct 5, 2022 · PreprintPlant Biology

Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration

M. Ambati, I. Apicella, S. Narendran, S.-b. Wang, H. Leung, F. Pereira, A. Varshney, M. Shadmehr, C. Stains, B. Werner, K. Baker, K. Marion, S. Sadda, E. Taylor, J. Magagnoli, , B. Gelfand

This paper identifies fluoxetine as a potential repurposed drug for dry AMD by showing it inhibits NLRP3-ASC inflammasome activation and reduces RPE degeneration in mice, supported by epidemiological data.

bioRxiv · Jan 11, 2021Immunology

cis dominantly explains regulatory divergence between two indica rice genotypes; drought further enhances regulatory differences

N. C. Ereful, A. Laurena, L.-y. Liu, S.-M. Kao, E. Tsai, M. Thomson, A. Greenland, W. Powell, I. Mackay, H. Leung

This study identifies cis and trans regulatory divergence between two indica rice genotypes under stress and non-stress conditions, showing cis dominance under normal conditions and increased trans effects under drought.

bioRxiv · Oct 18, 2020 · PreprintPlant Biology