Cell BiologybioRxiv
Mutant p53 triggers a dynamin-1/APPL1 endosome feedback loop that regulates β1 integrin recycling and migration
A. M. Lakoduk, P. Roudot, M. Mettlen…·S. L. Schmid
This study identifies a feedback loop involving mutant p53, dynamin-1, and APPL1 endosomes that enhances β1 integrin recycling and cell migration in cancer.
DOI 10.1083/jcb.201810183