Author

H. Mochizuki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. Aguirre· 2 shared D. Motooka· 2 shared D. Okuzaki· 2 shared H. Ogi· 2 shared K. Ikenaka· 2 shared K. Nakajima· 2 shared K. Yamaguchi· 2 shared M. Arai· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

C. Aguirre

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Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivMay 9, 2023

Single-cell transcriptome landscape of circulating CD4+ T cell populations in human autoimmune diseases

Y. Yasumizu, D. Takeuchi, R. Morimoto…·S. Sakaguchi

The paper identifies 12 transcriptional gene programs in CD4+ T cells from autoimmune diseases and shows their utility in disease characterization and prediction.

DOI 10.1016/j.xgen.2023.100473

humanscRNA-seq

𝕏 PostBluesky

BiophysicsbioRxivPreprintFeb 10, 2022

Conformational switch in the alpha-synuclein C-terminus domain directs its fibril polymorphs

C. Aguirre, Y. Miyanoiri, M. So…·H. Mochizuki

This study identifies a conformational switch in the alpha-synuclein C-terminus domain that determines fibril polymorphs by altering morphology in response to ionic strength and temperature.

DOI 10.1101/2022.02.10.479831

humanprotein structure

𝕏 PostBluesky

BiophysicsbioRxivFeb 1, 2022

Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis

K. Nakajima, K. Yamaguchi, M. Noji…·Y. Goto

This study identifies serum albumin concentration as a tertiary risk factor for dialysis-related amyloidosis, showing that maintenance dialysis improves outcomes by increasing serum component concentrations.

DOI 10.1038/s41467-022-33247-3

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivDec 19, 2021

Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma

Y. Yasumizu, N. Ohkura, H. Murata…·H. Mochizuki

This study identifies neuromuscular gene expression in thymoma-associated myasthenia gravis by analyzing bulk and single-cell RNA-seq data, linking it to specific thymic epithelial cell subpopulations.

DOI 10.1038/s41467-022-31951-8

humanbulk RNA-seq

𝕏 PostBluesky