Author

M. Noji

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

C. Mesaros· 2 shared K. E. Wellen· 2 shared L. Izzo· 2 shared S. Trefely· 2 shared Y. Goto· 2 shared A. Bostwick· 1 shared B. E. Schaffer· 1 shared C. Aguirre· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Mesaros

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis

K. Nakajima, K. Yamaguchi, M. Noji, C. Aguirre, K. Ikenaka, H. Mochizuki, L. Zhou, H. Ogi, T. Ito, I. Narita, F. Gejyo, H. Naiki, S. Yamamoto, Y. Goto

This study identifies serum albumin concentration as a tertiary risk factor for dialysis-related amyloidosis, showing that maintenance dialysis improves outcomes by increasing serum component concentrations.

bioRxiv · Feb 1, 2022Biophysics

Glutamine deprivation triggers NAGK-dependent hexosamine salvage

S. L. Campbell, C. Mesaros, L. Izzo, H. Affronti, T. Tsang, M. Noji, B. E. Schaffer, K. Sun, S. Trefely, S. Kruijning, J. Blenis, I. A. Blair, K. E. Wellen

This study shows that glutamine deprivation in pancreatic ductal adenocarcinoma cells increases free GlcNAc and activates NAGK-dependent hexosamine salvage to support tumor growth.

bioRxiv · Sep 13, 2020Cancer Biology

Quantitative sub-cellular acyl-CoA analysis reveals distinct nuclear regulation

S. Trefely, K. Huber, J. Liu, M. Noji, S. Stransky, J. Singh, M. Doan, C. D. Lovell, E. von Krusenstiern, H. Jiang, A. Bostwick, H. L. Pepper, L. Izzo, S. Zhao, J. P. Xu, , N. W. Snyder

The paper introduces SILEC-SF, a method for sub-cellular metabolomic analysis, and finds distinct nuclear acyl-CoA profiles with notable propionyl-CoA enrichment and a new metabolic pathway for histone propionylation.

bioRxiv · Jul 30, 2020 · PreprintBiochemistry

Multistep changes in amyloid structure that are induced by cross-seeding on a rugged energy landscape

K. Yuzu, N. Yamamoto, M. Noji, M. So, Y. Goto, T. Iwasaki, M. Tsubaki, E. Chatani

This study investigates how cross-seeding of insulin amyloid fibrils from different species leads to structural changes and new amyloid forms with distinct properties.

bioRxiv · Jul 19, 2020Biochemistry