Author

H. Roberts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Briley· 1 shared A. Mangoli· 1 shared A. Mitoubsi· 1 shared B. T. Whitfield· 1 shared C. Fernandez-del Castillo· 1 shared C. Fraley· 1 shared C. J. Pirozzi· 1 shared C. Shiau· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Briley

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis

C. Shiau, J. Cao, M. T. Gregory, D. Gong, X. Yin, J.-W. Cho, P. L. Wang, J. Su, S. Wang, J. W. Reeves, T. K. Kim, Y. Kim, J. A. Guo, N. A. Lester, N. Schurman, , W. L. Hwang

This study uses single-cell spatial transcriptomics and optimal transport analysis to reveal therapy-induced changes in pancreatic cancer microenvironment interactions.

bioRxiv · Jun 28, 2023 · PreprintCancer Biology

Cdc42 prevents precocious Rho1 activation during cytokinesis in a Pak1-dependent manner

U. N. Onwubiko, E. Koory, S. Pokharel, H. Roberts, A. Mitoubsi, M. E. Das

This study shows that Cdc42 prevents early Rho1 activation during cytokinesis in fission yeast, ensuring proper timing of septum formation and cytokinesis fidelity through Pak1-dependent regulation.

Journal of Cell Science · Apr 26, 2023Peer-reviewedCell Biology

Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas

S. Hariharan, B. T. Whitfield, C. J. Pirozzi, M. S. Waitkus, M. C. Brown, M. L. Bowie, D. M. Irvin, K. Roso, R. Fuller, J. Hostettler, S. Dharmaiah, E. A. Gibson, A. Briley, A. Mangoli, C. Fraley, , D. M. Ashley

This study shows that ATRX loss primes glioma cells for innate immune recognition, while IDH1R132H mutation suppresses immune signaling, which can be reversed by IDH1 inhibition.

bioRxiv · Apr 20, 2023 · PreprintCancer Biology