Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
R. Lipsh-Sokolik, O. Khersonsky, S. P. Schroder…·S. J. Fleishman
The paper introduces CADENZ, a machine-learning strategy for designing structurally diverse enzymes, achieving a tenfold improved hit rate and over 10,000 active enzymes.
K. Marneth, H. van den Elst, A. Cramer-Blok…·F. Ben Bdira
This study modifies a GH11 xylanase to enhance transglycosylation by increasing thumb flexibility through a point mutation, altering its enzymatic balance and dynamics.
T. van der Wel, R. Hilhorst, H. den Dulk…·M. van der Stelt
The paper uses a chemical genetics strategy to study FES kinase target engagement in human cells, revealing its role in neutrophil phagocytosis via SYK activation.
F. Ben Bdira, C. A. Waudby, A. N. Volkov…·M. Ubbink
The paper shows that the rigid xylanase enzyme uses substrate flexibility to facilitate catalysis without significant structural changes.
C. Araman, L. Pieper-Pournara, T. van Leeuwen…·S. I. van Kasteren
The paper explores how bioorthogonal antigens can be used to study antigen processing and presentation without bias.