MicrobiologybioRxiv
The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells
X. Zhuang, S. Tsukuda, F. Wrensch…·J. A. McKeating
This study shows BMAL1 regulates ACE2 expression and SARS-CoV-2 entry in lung epithelial cells, with SR9009 reducing viral replication through circadian mechanisms.
DOI 10.1016/j.isci.2021.103144