Author

H. Borrmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 1

Frequent Co-Authors

J. A. McKeating· 3 shared M. Schilling· 3 shared X. Zhuang· 3 shared J. M. Harris· 2 shared P. Balfe· 2 shared P. Borrow· 2 shared A. Ashton· 1 shared A. E. Kliszczak· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

J. A. McKeating

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3 papers

Recent·Most cited

Circadian regulation of human immunodeficiency virus type 1 replication

H. Borrmann, G. Ulkar, A. E. Kliszczak, D. Ismed, M. Schilling, A. Magri, J. M. Harris, P. Balfe, S. Vasudevan, P. Borrow, X. Zhuang, J. A. McKeating

This study shows HIV-1 replication is regulated by circadian rhythms through interactions between transcription factors BMAL1, REV-ERB, and ROR, with implications for HIV therapy.

bioRxiv · Nov 30, 2022 · PreprintMicrobiology

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

X. Zhuang, S. Tsukuda, F. Wrensch, P. A. Wing, M. Schilling, J. M. Harris, H. Borrmann, S. B. Morgan, J. L. Cane, L. Mailly, N. Thakur, C. Conceicao, H. Sanghani, L. Heydmann, C. Bach, , J. A. McKeating

This study shows BMAL1 regulates ACE2 expression and SARS-CoV-2 entry in lung epithelial cells, with SR9009 reducing viral replication through circadian mechanisms.

bioRxiv · Mar 20, 2021Microbiology

Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication

H. Borrmann, R. Davies, M. Dickinson, I. Pedroza-Pacheco, M. Schilling, A. Vaughan-Jackson, W. James, P. Balfe, P. Borrow, J. A. McKeating, X. Zhuang

This study shows that REV-ERB agonists inhibit HIV-1 replication by suppressing its promoter activity in multiple cell types.

Scientific Reports · Aug 6, 2020Peer-reviewedMicrobiology