Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination.
H. Voic, R. D. de Vries, J. Sidney, P. Rubiro, E. Moore, E. J. Phillips, S. Mallal, B. Schwan, D. Weiskopf, A. Grifoni, A. Sette
This study identifies and characterizes CD4+ T cell epitopes specific to Shingrix vaccination, showing a shift in immunodominance from non-structural proteins to gE and mapping HLA restrictions for these epitopes.
bioRxiv · Jul 29, 2020Immunology