S. Mallal

Cytokine and Chemokine Receptor Profiles in Adipose Tissue Vasculature Unravel Endothelial Cell Responses in HIV

This study examines cytokine and chemokine receptor expression in adipose tissue endothelial cells of HIV-positive individuals, identifying receptor differences and their potential role in vascular dysfunction.

Discovery of post-translationally modified self-peptides that promote hypertension

The paper identifies post-translationally modified self-peptides linked to hypertension using a combined computational and experimental approach.

Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

This study identifies T cell epitopes and cross-reactivity patterns across common cold coronaviruses, highlighting conservation and limitations in cross-reactivity among subgenera.

White Adipose Tissue Compositional and Transcriptional Patterns with Progressive Glucose Intolerance in Persons with HIV

The paper examines compositional and transcriptional changes in subcutaneous adipose tissue of HIV-positive individuals with varying glucose intolerance, identifying shared patterns with HIV-negative diabetics.

SARS-CoV-2 vaccination induces immunological memory able to cross-recognize variants from Alpha to Omicron

This study shows that SARS-CoV-2 vaccines induce T cell responses that cross-recognize variants from Alpha to Omicron, with high preservation of CD4+ and CD8+ T cell epitopes.

Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

The paper identifies SARS-CoV-2 epitopes recognized by CD4+ and CD8+ T cells in COVID-19 patients and develops epitope megapools for their detection.

Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination.

This study identifies and characterizes CD4+ T cell epitopes specific to Shingrix vaccination, showing a shift in immunodominance from non-structural proteins to gE and mapping HLA restrictions for these epitopes.

Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level

The paper identifies a novel SARS-CoV-2 sub-genomic RNA generated by homologous recombination involving the R203K/G204R variant in nucleocapsid, which may enhance viral adaptation and expression.