Author

H.-H. Lu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C.-J. Yu· 2 shared H.-C. Tsai· 2 shared R. R. Weng· 2 shared S.-Y. Lin· 2 shared Y.-H. Juan· 2 shared Y.-J. Huang· 2 shared Z.-C. Hung· 2 shared A. Vasquez Ayala· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

C.-J. Yu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Commensal bacteria promote type I interferon signaling to maintain immune tolerance

A. Vasquez Ayala, C.-Y. Hsu, K. Matsuo, E. Buzun, M. Carrillo Terrazas, L. R. Loomis, H.-H. Lu, J.-H. Park, P. Rivaud, M. Thomson, H. Chu

This study shows that commensal bacteria promote type I interferon signaling to support immune tolerance by enhancing T regulatory cell function.

bioRxiv · Oct 21, 2021 · PreprintImmunology

Epigenetic therapy remodels the immune synaptic cytoskeleton to potentiate cancer susceptibility to γδ T cells

R. R. Weng, H.-H. Lu, C.-T. Lin, C.-C. Fan, R.-S. Lin, T.-C. Huang, S.-Y. Lin, Y.-J. Huang, Y.-H. Juan, Y.-C. Wu, Z.-C. Hung, C. Liu, X.-H. Lin, W.-C. Hsieh, T.-Y. Chiu, , H.-C. Tsai

DNA methyltransferase inhibitors enhance γδ T cell-mediated lung cancer killing by remodeling immune synaptic cytoskeletal networks.

bioRxiv · Apr 30, 2020 · PreprintCancer Biology

Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma

H.-H. Lu, S.-Y. Lin, R. R. Weng, Y.-H. Juan, Y.-W. Chen, H.-H. Hou, Z.-C. Hung, G. A. Oswita, Y.-J. Huang, J.-Y. Shih, C.-J. Yu, H.-C. Tsai

This study identifies FUT4 as a key driver of lung adenocarcinoma metastasis through aberrant fucosylation of proteins involved in cell signaling and trafficking, showing its potential as a therapeutic target.

bioRxiv · Nov 11, 2019Cancer Biology