Author

Y.-W. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 2 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:organoid / primary culture· 2

Frequent Co-Authors

H.-W. Snoeck· 2 shared J. Wang· 2 shared A. Das· 1 shared A. J. Bittel· 1 shared A. Saqi· 1 shared A. Strikoudis· 1 shared B. Diaz· 1 shared B. Grubbs· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCell Biology

H.-W. Snoeck

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Engraftment and injury repair in regionally conditioned rat lung in vivo by lung progenitors derived from human pluripotent stem cells.

H.-Y. Liu, C. Predella, Y.-W. Chen, J. Wang, S. Fare, M. G. Pezet, S. Liang, A. Saqi, J. W. Murray, G. Vunjak-Novakovic, H.-W. Snoeck, N. V. Dorrello

This study demonstrates that human pluripotent stem cell-derived progenitors can engraft in rat lungs and promote injury repair while preventing conditioning-induced damage.

bioRxiv · Nov 28, 2023 · PreprintCell Biology

The respiratory enzyme complex Rnf is vital for metabolic adaptation and virulence in Fusobacterium nucleatum

T. A. Britton, C. Wu, Y.-W. Chen, D. Franklin, Y. Chen, M. I. Camacho, T. T. Luong, A. Das, H. Ton-That

This paper identifies the Rnf complex as essential for Fusobacterium nucleatum's metabolic adaptation and virulence, showing its role in amino acid catabolism, biofilm formation, and pathogenesis in a mouse model.

bioRxiv · Jun 13, 2023 · PreprintMicrobiology

Facioscapulohumeral muscular dystrophy is associated with altered myoblast proteome dynamics

Y. Nishimura, A. J. Bittel, C. A. Stead, Y.-W. Chen, J. G. Burniston

This study uses proteomic analysis to show that FSHD myoblasts have altered mitochondrial protein abundance and turnover rates compared to unaffected siblings.

bioRxiv · Dec 14, 2022Cell Biology

Triple Notch/Tgfβ/FoxO1 blockade converts multiple intestinal sub-lineages into β-like cells and lowers glycemia in diabetic animals

W. Du, J. Wang, T. Kuo, L. Wang, W. McKimpson, J. Son, H. Watanabe, T. Kitamoto, L. Yunkyoung, L. Ratner, K. McCune, Y.-W. Chen, B. Grubbs, M. Thornton, J. Fan, , D. Accili

bioRxiv · Mar 21, 2022 · PreprintCell Biology

Cytoplasmic tail truncation of SARS-CoV-2 Spike protein enhances titer of pseudotyped vectors but masks the effect of the D614G mutation

H.-Y. Chen, C. Huang, L. Tian, X. Huang, C. Zhang, G. N. Llewellyn, G. L. Rogers, K. Andresen, M. R. G. O'Gorman, Y.-W. Chen, P. M. Cannon

This study shows that truncating the SARS-CoV-2 Spike protein's cytoplasmic tail increases pseudovector titer but masks the D614G mutation's effect on Spike incorporation.

bioRxiv · Jun 21, 2021Microbiology

Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma

H.-H. Lu, S.-Y. Lin, R. R. Weng, Y.-H. Juan, Y.-W. Chen, H.-H. Hou, Z.-C. Hung, G. A. Oswita, Y.-J. Huang, J.-Y. Shih, C.-J. Yu, H.-C. Tsai

This study identifies FUT4 as a key driver of lung adenocarcinoma metastasis through aberrant fucosylation of proteins involved in cell signaling and trafficking, showing its potential as a therapeutic target.

bioRxiv · Nov 11, 2019Cancer Biology

Modeling of fibrotic lung disease using 3D organoids derived from human pluripotent stem cells

H.-W. Snoeck, A. Strikoudis, L. Loffredo, Y.-W. Chen

This study uses hPSC-derived 3D lung organoids to model fibrotic lung disease, identifying IL-11 as a potential therapeutic target for IPF and HPSIP.

bioRxiv · Feb 3, 2019Pathology