Author

C.-Y. Hsu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 3 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

H. Chu· 4 shared E. Buzun· 3 shared A. Vasquez Ayala· 2 shared J. Zhao· 2 shared L. R. Loomis· 2 shared M. Carrillo Terrazas· 2 shared A. Bauermeister· 1 shared A. D. Patterson· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersMicrobiology

H. Chu

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

A bacterial sialidase mediates early life colonization by a pioneering gut commensal

E. Buzun, C.-Y. Hsu, K. Sejane, R. E. Oles, A. V. Ayala, L. R. Loomis, J. Zhao, L.-A. Rossitto, D. McGrosso, D. J. Gonzalez, L. Bode, H. Chu

This study identifies a bacterial sialidase, NanH, in Bacteroides fragilis that mediates early gut colonization and resilience through host-derived glycans.

bioRxiv · Aug 8, 2023Microbiology

A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data

S. Zuffa, R. Schmid, A. Bauermeister, P. W. P. Gomes, A. M. Caraballo-Rodriguez, Y. El Abiead, A. T. Aron, E. C. Gentry, J. Zemlin, M. J. Meehan, N. E. Avalon, R. H. Cichewicz, E. Buzun, M. Carrillo Terrazas, C.-Y. Hsu, , Escud

MicrobeMASST identifies microbial-derived metabolites and their producers using taxonomically-informed mass spectrometry data without prior knowledge.

bioRxiv · Jul 20, 2023 · PreprintMicrobiology

Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity

C.-H. Lin, C.-J. Wu, S. Cho, R. Patkar, L.-L. Lin, M.-C. Chen, E. Israelsson, J. Betts, M. Niedzielska, S. A. Patel, H. G. Duong, R. R. Gerner, C.-Y. Hsu, M. Catley, R. A. Maciewicz, , L.-F. Lu

This study identifies intestinal regulatory T cells producing IL-27 to specifically regulate Th17 immunity in the gut, revealing a novel mechanism for tissue-specific immune control.

bioRxiv · Feb 20, 2023Immunology

Commensal bacteria promote type I interferon signaling to maintain immune tolerance

A. Vasquez Ayala, C.-Y. Hsu, K. Matsuo, E. Buzun, M. Carrillo Terrazas, L. R. Loomis, H.-H. Lu, J.-H. Park, P. Rivaud, M. Thomson, H. Chu

This study shows that commensal bacteria promote type I interferon signaling to support immune tolerance by enhancing T regulatory cell function.

bioRxiv · Oct 21, 2021 · PreprintImmunology

Molecular insights into substrate recognition and discrimination by the N-terminal domain of Lon AAA+ protease

S.-R. Tzeng, Y.-C. Tseng, C.-C. Lin, C.-Y. Hsu, S.-J. Huang, Y.-T. Kuo, C.-I. Chang

This study investigates how the N-terminal domain of Lon AAA+ protease recognizes and discriminates substrates through hydrophobic patches and flexible linkers.

eLife · Apr 30, 2021Peer-reviewedBiochemistry

Comprehensive molecular characterization of pediatric treatment-induced high-grade glioma: A distinct entity despite disparate etiologies with defining molecular characteristics and potential therapeutic targets

J. DeSisto, J. T. Lucas, K. Xu, A. Donson, T. Lin, B. Sanford, Q. T. Tran, D. Hedges, C.-Y. Hsu, G. T. Armstrong, M. Arnold, S. Bhatia, P. Flannery, R. Lemma, L. Hardie, , A. L. Green

This study characterizes treatment-induced high-grade gliomas (TIHGGs) through molecular profiling, identifying distinct subgroups and potential therapeutic targets.

bioRxiv · Oct 29, 2019 · PreprintCancer Biology

Using the modified male osteoporosis self-assessment tool for Taiwan to predict osteoporosis onset - a sub-study of the Taiwan osteoporosis survey

Y.-C. Chen, D.-H. Liu, T.-T. Cheng, J.-F. Chen, S.-F. Yu, W.-C. Chiu, C.-Y. Hsu

The paper develops and validates a modified osteoporosis risk index (MOSTAi) for male Taiwanese patients, showing it outperforms existing tools in predicting osteoporosis onset.

bioRxiv · Nov 26, 2018 · PreprintImmunology

Division of labor during biofilm matrix production

A. Dragos, H. T. Kiesewalter, M. Martin, C.-Y. Hsu, R. Hartmann, T. Wechsler, C. Eriksen, S. Brix Pedersen, K. Drescher, N. Stanley-Wall, R. Kummerli, A. T. Kovacs

This study shows that genetic division of labor in Bacillus subtilis enhances biofilm productivity by allowing specialized mutants to exchange matrix components, outperforming phenotypic specialization.

bioRxiv · Mar 13, 2018Microbiology