BiophysicsbioRxiv
Cholesterol promotes both head group visibility and clustering of PI(4,5)P2 driving unconventional secretion of Fibroblast Growth Factor 2
F. Lolicato, R. Saleppico, A. Griffo…·W. Nickel
This study shows cholesterol enhances FGF2 secretion by promoting PI(4,5)P2 clustering and membrane pore formation.
DOI 10.1083/jcb.202106123